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Virtual Event
November 17–November 20, 2020
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Friday, November 20 • 3:10pm - 3:45pm
Return of the Kraken: Bioinformatics at Scale with Kubernetes - Cab Maddux, Day Zero Diagnostics

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Kraken, the legendary sea monster of Scandinavian lore, whose supposed size and appearance would strike fear into the toughest of Nordic sailors, has nothing on the Johns Hopkins-developed taxonomic sequence classification bioinformatics tool that shares its name. A complex C++ and Perl codebase, coupled with an intense resource footprint - including requiring 220G of RAM at runtime - makes applying Kraken reliably at scale as daunting as meeting a colossal cephalopod on open water. In this talk, we’ll discuss how we’re using Kubernetes, Prometheus and Helm at Day Zero Diagnostics to run complex, research-oriented bioinformatics tools, like Kraken, to support the rapid profiling of pathogenic bacteria at scale. More broadly, we’ll address the growing intersection of complex, specialized academic software and its non-academic application at scale with modern tooling and infrastructure.

Speakers
avatar for Cab Maddux

Cab Maddux

Day Zero Diagnostics
Cab leads the software team at Day Zero Diagnostics (DZD), a Boston-based startup modernizing infectious disease diagnosis with machine learning and next generation sequencing. Prior to DZD, Cab helped scale engineering at Vancouver-based health-tech startup QxMD through acquisition... Read More →



Friday November 20, 2020 3:10pm - 3:45pm EST
Intrado Virtual Event Platform